Pre-Clinical Toxicology Support
- Study Data Review and Analysis
- Report Preparation
- Peer Review
- Risk Characterization
- Comparative Risk
Over 250 Chemicals of Interest,
including:
Benzene Bisphenol-A (BPA)
Chlorinated solvents DEHP
1,2-Dichloroethane Formaldehyde Lead
Metals
Methylene chloride Perchloroethylene (PERC)
Phthalates
Terephthalic acid Toluene Trichloroethylene (TCE) Xylene
...and many more
Drugs of Interest include: Alcohol
Botox (e.g., Botulinum neurotoxin Type A) Ciprofloxacin Cocaine Cyclosporine A
Demerol
Dilantin
Keflex (i.e., Cephalosporin)
Levaquin
Librium Lithium
Mellaril
Methadone
Mineral Oil Morphine
Penicillin
Prilosec
Progesterone
Prozac (fluoxetine)
Soma
Viagra
Xanax (alprazolam)
Zyprexa (olanzapine) ...and many more
Acute Respiratory Distress Syndrome (ARDS)
Bisphenol-A (BPA)
Children's Health
Endocrine Disruption
Lead
Morphine Intoxication
Random Drug Testing
Rhabdomyolysis
Sewer Gas
Stevens-Johnson Syndrome
Toxic-Epidermal Necrolysis
Regulatory Submissions and Responses
-- EPA, FDA
Monitoring -- scientific conferences, workshops and regulatory agency meetings
Examples of
Past Projects
Expert Witness and litigation support since
1998, including deposition and jury trial testimony, for Defense and Plaintiff in toxicology,
carcinogenesis (cancer causation), pharmacology, and pharmacy standards of
care.
Expert technical report preparation in
support of company responses to FDA and EPA requests.
Provided expert professional advice at
strategy sessions on environmental regulatory policies and considerations.
A review of chemical contaminants in
food, water and breast milk.
A review of published studies that do not
support the endocrine disruption hypothesis.
A report on the lack of consensus on
endocrine disruption.
Poster presentations and poster
monitoring at the International Symposiums on Environmental Endocrine
Disruptors in Japan ('99 and '00).
...and many more.
Relevant
Scientific Publications
Milman, H.A., Bosland, M.C., Walden, P.D. and Heinze, J.E.:
Evaluation of the adequacy of published studies of low dose effects of bisphenol A (BPA) on the rodent prostate for use in human risk
assessment. Regul. Toxicol. Pharmacol. 35:338-346 (2002).
Milman, H.A., and Heinze, J.E.: Evaluation of the
relationship between children's health and exposure to endocrine
disrupters. Abstracts, 3rd Annual Meeting of the Japan Society of
Endocrine Disrupters Research. PE-18:336 (2000).
Over 70 peer reviewed, scientific publications and
abstracts and numerous governmental reports (see PUBLICATIONS).